PLATELETS AND THROMBOPOIESIS Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
نویسندگان
چکیده
1Department of Vascular Medicine, University Clinic, University of Würzburg and Rudolf Virchow Center, DFG Research Center for Experimental Biomedicine, Würzburg, Germany; 2Inserm UMR-S949, Université de Strasbourg, Etablissement Français du Sang (EFS)–Alsace, Strasbourg, France; and 3Biotec Research and Information Centre (BRIC), Biomedical Institute, University of Copenhagen, Copenhagen, Denmark
منابع مشابه
Rac and Cdc42 team up for platelets.
P latelets, the anucleate progeny of bone marrow megakaryocytic cells, are well known as the primary cellular agents of hemostasis. Pioneering efforts over the past decade have visualized the manner in which megakaryocytes give rise to platelets through a carefully orchestrated branching, budding, and release of proplatelet appendages. In their later stages of maturation, megakaryocytes extend ...
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